5KZY
Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with cyclopamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Smoothened | polymer | 121 | 13402.4 | 2 | UniProt (Q98SW5) Pfam (PF01392) | Xenopus laevis (African clawed frog) | |
| 2 | C, D (A, B) | Cyclopamine | non-polymer | 411.6 | 2 | Chemie (CY8) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B: 35 - 154 (UniProt: Q98SW5)
| PDB | External Database | Details |
|---|---|---|
| Gly 34 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26804.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 823.2 | |
| All* | Total formula weight | 27628.0 |
