5KYC
Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin (malonate bound)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Ubiquitin carboxyl-terminal hydrolase 7 | polymer | 351 | 40617.9 | 1 | UniProt (Q93009) Pfam (PF00443) In PDB | Homo sapiens (Human) | Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7 |
| 2 | C | Polyubiquitin-B | polymer | 76 | 8576.8 | 1 | UniProt (P0CG47) Pfam (PF00240) In PDB | Homo sapiens (Human) | |
| 3 | B | MALONIC ACID | non-polymer | 104.1 | 1 | Chemie (MLA) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 500 | Chemie (HOH) |
Sequence modifications
B: 208 - 554 (UniProt: Q93009)
| PDB | External Database | Details |
|---|---|---|
| Gly 204 | - | expression tag |
| Ser 205 | - | expression tag |
| His 206 | - | expression tag |
| Met 207 | - | expression tag |
| Lys 302 | Val 286 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49194.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 49483.0 |
