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5KVL

Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Humanized 10G4 anti-Leukotriene C4 Immunoglobulin G (IgG) heavy chain Fab fragmentpolymer21522847.51Homo sapiens (Human)
2B
(L)
Humanized 10G4 anti-Leukotriene C4 Immunoglobulin G (IgG) light chainpolymer21423439.11Homo sapiens
3C, H, I
(H, L)
ZINC IONnon-polymer65.43Chemie (ZN)
4D
(H)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5E
(H)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
6F
(H)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
7G
(H)
(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acidnon-polymer625.81Chemie (LTX)
8J, K
(H, L)
waterwater18.0363Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight46286.6
Non-Polymers*Number of molecules7
Total formula weight1156.4
All*Total formula weight47443.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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