5KVL

Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue ZN H 301

Chain	Residue
H	HIS162
H	HOH417
H	HOH566
L	ASN138
L	HOH402
L	HOH500
L	HOH535

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site_id	AC2
Number of Residues	4
Details	binding site for residue EDO H 302

Chain	Residue
H	GLY172
H	LEU173
H	LYS115
H	PHE144

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site_id	AC3
Number of Residues	5
Details	binding site for residue PGE H 303

Chain	Residue
H	GLN39
H	PHE40
H	LYS43
H	VAL92
L	GLN38

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site_id	AC4
Number of Residues	9
Details	binding site for residue TRS H 304

Chain	Residue
H	PHE40
H	ASN153
H	ALA156
H	LEU157
H	GLN190
H	HOH401
H	HOH412
H	HOH427
H	HOH541

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site_id	AC5
Number of Residues	16
Details	binding site for residue LTX H 305

Chain	Residue
H	TYR33
H	SER34
H	TYR52
H	PRO98
H	ARG99
H	TRP101
H	HOH443
H	HOH453
H	HOH454
H	HOH511
H	HOH569
L	ARG46
L	TYR49
L	TYR91
L	ARG96
L	HOH408

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site_id	AC6
Number of Residues	2
Details	binding site for residue ZN L 301

Chain	Residue
L	ASP151
L	HIS189

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site_id	AC7
Number of Residues	1
Details	binding site for residue ZN L 302

Chain	Residue
L	HIS189

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR192-HIS198

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