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5KU6

Crystal structure for the complex of human carbonic anhydrase IV and methazolamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DCarbonic anhydrase 4polymer26630364.54UniProt (P22748)
Pfam (PF00194)
In PDB
Homo sapiens (Human)Carbonate dehydratase IV,Carbonic anhydrase IV,CA-IV
2A, B, C, DN-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamidenon-polymer236.34Chemie (MZM)
3A, B, C, DZINC IONnon-polymer65.44Chemie (ZN)
4D, A, B, CSULFATE IONnon-polymer96.18Chemie (SO4)
5A, B, CGLYCEROLnon-polymer92.15Chemie (GOL)
6D, B, CACETATE IONnon-polymer59.03Chemie (ACT)
7waterwater18.0915Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight121457.9
Non-Polymers*Number of molecules24
Total formula weight2612.8
All*Total formula weight124070.7
*Water molecules are not included.

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PDB entries from 2024-07-24

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