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5KIJ

Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasepolymer45252030.11UniProt (Q9UKM7)
Pfam (PF01532)
Homo sapiens (Human)ER alpha-1,2-mannosidase,ER mannosidase 1,ERMan1,Man9GlcNAc2-specific-processing alpha-mannosidase,Mannosidase alpha class 1B member 1
2B
(B)
alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1518.31In PDB
GlyTouCan (G51034LA)
3C
(A)
LANTHANUM (III) IONnon-polymer138.91Chemie (LA)
4D, E
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
5F, G, I, J
(A)
1,4-BUTANEDIOLnon-polymer90.14Chemie (BU1)
6H
(A)
3-PYRIDINIUM-1-YLPROPANE-1-SULFONATEnon-polymer201.21Chemie (1PS)
7K
(A)
waterwater18.0605Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight52030.1
BranchedNumber of molecules1
Total formula weight1518.3
Non-Polymers*Number of molecules8
Total formula weight892.8
All*Total formula weight54441.2
*Water molecules are not included.

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PDB entries from 2026-01-21

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