5KIJ
Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase | polymer | 452 | 52030.1 | 1 | UniProt (Q9UKM7) Pfam (PF01532) | Homo sapiens (Human) | ER alpha-1,2-mannosidase,ER mannosidase 1,ERMan1,Man9GlcNAc2-specific-processing alpha-mannosidase,Mannosidase alpha class 1B member 1 |
| 2 | B (B) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1518.3 | 1 | In PDB GlyTouCan (G51034LA) | |||
| 3 | C (A) | LANTHANUM (III) ION | non-polymer | 138.9 | 1 | Chemie (LA) | |||
| 4 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F, G, I, J (A) | 1,4-BUTANEDIOL | non-polymer | 90.1 | 4 | Chemie (BU1) | |||
| 6 | H (A) | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE | non-polymer | 201.2 | 1 | Chemie (1PS) | |||
| 7 | K (A) | water | water | 18.0 | 605 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52030.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1518.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 892.8 | |
| All* | Total formula weight | 54441.2 |






