5KH6
SETDB1 in complex with a fragment candidate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETDB1 | polymer | 211 | 24627.4 | 1 | UniProt (Q15047) Pfam (PF18300) Pfam (PF18359) Pfam (PF18358) | Homo sapiens (Human) | ERG-associated protein with SET domain,ESET,Histone H3-K9 methyltransferase 4,H3-K9-HMTase 4,Lysine N-methyltransferase 1E,SET domain bifurcated 1 |
| 2 | B, D, O, T (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | E, F, G, H, I (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | J, K, L, M (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | N (A) | methyl 3-(methylsulfonylamino)benzoate | non-polymer | 229.3 | 1 | Chemie (6SU) | |||
| 7 | P, Q, R (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 8 | S (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 9 | U (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 10 | V (A) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 196 - 400 (UniProt: Q15047)
| PDB | External Database | Details |
|---|---|---|
| Glu 190 | - | expression tag |
| Asn 191 | - | expression tag |
| Leu 192 | - | expression tag |
| Tyr 193 | - | expression tag |
| Phe 194 | - | expression tag |
| Gln 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24627.4 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1647.3 | |
| All* | Total formula weight | 26274.7 |
