5KH6
SETDB1 in complex with a fragment candidate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | GLN273 |
| A | VAL274 |
| A | TRP275 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 502 |
| Chain | Residue |
| A | GLY300 |
| A | TYR301 |
| A | GLU386 |
| A | ARG394 |
| A | 6SU513 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | LYS208 |
| A | LYS211 |
| A | LEU242 |
| A | HIS246 |
| A | HOH693 |
| A | LYS207 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | HIS214 |
| A | LYS215 |
| A | HOH606 |
| A | HOH618 |
| A | HOH619 |
| A | HOH648 |
| A | HOH658 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | ASP270 |
| A | GLY271 |
| A | ASN272 |
| A | GLN273 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | THR306 |
| A | GLN307 |
| A | SER308 |
| A | ARG384 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 507 |
| Chain | Residue |
| A | ARG203 |
| A | HOH637 |
| A | HOH715 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 508 |
| Chain | Residue |
| A | PRO316 |
| A | LYS318 |
| A | HOH634 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 509 |
| Chain | Residue |
| A | ARG209 |
| A | LYS364 |
| A | ASP381 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 510 |
| Chain | Residue |
| A | LYS318 |
| A | SER350 |
| A | EDO514 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 511 |
| Chain | Residue |
| A | SER243 |
| A | HIS246 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 512 |
| Chain | Residue |
| A | GLY225 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue 6SU A 513 |
| Chain | Residue |
| A | PHE296 |
| A | GLY300 |
| A | ALA302 |
| A | SER328 |
| A | CYS329 |
| A | PHE332 |
| A | TYR389 |
| A | DMS502 |
| A | HOH660 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 514 |
| Chain | Residue |
| A | ASN245 |
| A | ARG315 |
| A | PRO316 |
| A | LEU317 |
| A | CL510 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 515 |
| Chain | Residue |
| A | LYS269 |
| A | TYR301 |
| A | ALA302 |
| A | TRP387 |
| A | HOH620 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 516 |
| Chain | Residue |
| A | GLU283 |
| A | ASN286 |
| A | LYS288 |
| A | TYR304 |
| A | ARG343 |
| A | GLY372 |
| A | SER373 |
| A | HOH719 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 517 |
| Chain | Residue |
| A | LYS290 |
| A | ARG292 |
| A | ASP371 |
| A | HOH724 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 518 |
| Chain | Residue |
| A | GLU190 |
| A | ASN191 |
| A | THR223 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 519 |
| Chain | Residue |
| A | SER303 |
| A | TYR304 |
| A | ASP371 |
| A | TRP387 |
| A | HOH640 |
| A | HOH650 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 520 |
| Chain | Residue |
| A | LYS208 |
| A | THR210 |
| A | THR212 |
| A | HIS214 |
| A | HOH743 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 63 |
| Details | Domain: {"description":"Tudor 1"} |
| Chain | Residue | Details |
