5KGN
1.95A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (2d)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | polymer | 534 | 58704.5 | 2 | UniProt (G5EFZ1) Pfam (PF01676) Pfam (PF06415) In PDB | Caenorhabditis elegans | iPGM,Cofactor-independent phosphoglycerate mutase homolog |
2 | C, D | macrocyclic peptide inhibitor | polymer | 13 | 1458.6 | 2 | synthetic construct | ||
3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
7 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
8 | water | water | 18.0 | 735 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 539 (UniProt: G5EFZ1)
PDB | External Database | Details |
---|---|---|
Lys 540 | - | expression tag |
Leu 541 | - | expression tag |
Ala 542 | - | expression tag |
Ala 543 | - | expression tag |
Ala 544 | - | expression tag |
Leu 545 | - | expression tag |
Glu 546 | - | expression tag |
His 547 | - | expression tag |
His 548 | - | expression tag |
His 549 | - | expression tag |
His 550 | - | expression tag |
His 551 | - | expression tag |
His 552 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 120326.2 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 544.4 | |
All* | Total formula weight | 120870.6 |