5KA2
Protein Tyrosine Phosphatase 1B YAYA (Y152A, Y153A) mutant, open state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 306 | 35360.3 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (Human) | Protein-tyrosine phosphatase 1B,PTP-1B |
2 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
3 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
5 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A: 1 - 301 (UniProt: P18031)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
His -3 | - | expression tag |
Met -2 | - | expression tag |
Ala -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 152 | Tyr 152 | engineered mutation |
Ala 153 | Tyr 153 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35360.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 519.0 | |
All* | Total formula weight | 35879.4 |