5K9I
Crystal structure of c-SRC in complex with a covalent lysine probe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proto-oncogene tyrosine-protein kinase Src | polymer | 286 | 32726.6 | 2 | UniProt (P00523) Pfam (PF07714) | Gallus gallus (Chicken) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | C, D (A, B) | 4-[(4-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-6-[(prop-2-yn-1-yl)carbamoyl]pyrimidin-2-yl}piperazin-1-yl)methyl]benzene-1-sulfonyl fluoride | non-polymer | 538.6 | 2 | Chemie (O44) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, B: 251 - 533 (UniProt: P00523)
| PDB | External Database | Details |
|---|---|---|
| Gly 248 | - | expression tag |
| His 249 | - | expression tag |
| Met 250 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65453.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1077.2 | |
| All* | Total formula weight | 66530.5 |
