5K5J
Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcriptional repressor CTCF | polymer | 117 | 13722.9 | 1 | UniProt (P49711) Pfam (PF00096) | Homo sapiens (Human) | 11-zinc finger protein,CCCTC-binding factor,CTCFL paralog |
| 2 | B (B) | DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*AP*C)-3') | polymer | 13 | 3912.6 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*TP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3') | polymer | 13 | 4032.6 | 1 | synthetic construct | ||
| 4 | D, E, F, G (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | H (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | I (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | J, K, L (A, B, C) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 378 - 489 (UniProt: P49711)
| PDB | External Database | Details |
|---|---|---|
| Gly 373 | - | expression tag |
| Pro 374 | - | expression tag |
| Leu 375 | - | expression tag |
| Gly 376 | - | expression tag |
| Ser 377 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 21668.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 416.7 | |
| All* | Total formula weight | 22084.8 |
