5K5J

Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	CYS381
A	CYS384
A	HIS397
A	HIS401

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 502

Chain	Residue
A	CYS409
A	CYS412
A	HIS425
A	HIS430

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 503

Chain	Residue
A	CYS442
A	HIS455
A	HIS460
A	CYS439

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 504

Chain	Residue
A	CYS469
A	CYS472
A	HIS485
A	HIS489

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 A 505

Chain	Residue
A	TYR392
A	ARG396
A	ARG399
A	TYR407
A	GLN418
A	SER419

---

site_id	AC6
Number of Residues	3
Details	binding site for residue ACT A 506

Chain	Residue
A	ARG479
A	GLN486
A	HOH606

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	22
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cyi..CharFtqsgtmkmHilqk.H

Chain	Residue	Details
A	CYS409-HIS430
A	CYS439-HIS460
A	CYS469-HIS489

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Zinc finger: {"description":"C2H2-type 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	23
Details	Zinc finger: {"description":"C2H2-type 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	23
Details	Zinc finger: {"description":"C2H2-type 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	22
Details	Zinc finger: {"description":"C2H2-type 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---