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5K5H

Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transcriptional repressor CTCFpolymer12214200.41UniProt (P49711)
Pfam (PF00096)
Homo sapiens (Human)11-zinc finger protein,CCCTC-binding factor,CTCFL paralog
2B
(B)
DNA (5'-D(*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*C)-3')polymer134042.61synthetic construct
3C
(C)
DNA (5'-D(*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*G)-3')polymer133904.51synthetic construct
4D, E, F, G
(A)
ZINC IONnon-polymer65.44Chemie (ZN)
5H, I, J
(A, B, C)
waterwater18.06Chemie (HOH)
Sequence modifications
A: 348 - 464 (UniProt: P49711)
PDBExternal DatabaseDetails
Gly 343-expression tag
Pro 344-expression tag
Leu 345-expression tag
Gly 346-expression tag
Ser 347-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight22147.6
Non-Polymers*Number of molecules4
Total formula weight261.6
All*Total formula weight22409.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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