5K5H

Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 501

Chain	Residue
A	CYS353
A	MET355
A	CYS356
A	HIS369
A	HIS373

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 502

Chain	Residue
A	CYS381
A	CYS384
A	HIS397
A	HIS401

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 503

Chain	Residue
A	CYS409
A	CYS412
A	HIS425
A	HIS430

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 504

Chain	Residue
A	CYS439
A	CYS442
A	HIS455
A	HIS460

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	22
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cyi..CharFtqsgtmkmHilqk.H

Chain	Residue	Details
A	CYS409-HIS430
A	CYS439-HIS460

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	ZN_FING: C2H2-type 4 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE351-HIS373

---

site_id	SWS_FT_FI2
Number of Residues	22
Details	ZN_FING: C2H2-type 5 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE379-HIS401

---

site_id	SWS_FT_FI3
Number of Residues	23
Details	ZN_FING: C2H2-type 6 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR407-HIS430

---

site_id	SWS_FT_FI4
Number of Residues	23
Details	ZN_FING: C2H2-type 7 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE437-HIS460

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	THR374

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER402

---