5K24

Crystal structure of the complex between phosphatase PRL-2 in the oxidized state with the Bateman domain of murine magnesium transporter CNNM3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein tyrosine phosphatase type IVA 2	polymer	183	20893.1	2	UniProt (O70274) Pfam (PF00102) In PDB	Mus musculus (Mouse)	Protein-tyrosine phosphatase 4a2,Protein-tyrosine phosphatase of regenerating liver 2,PRL-2
2	C, D	Metal transporter CNNM3	polymer	153	17341.8	2	UniProt (Q32NY4) Pfam (PF00571) In PDB	Mus musculus (Mouse)	Ancient conserved domain-containing protein 3,mACDP3,Cyclin-M3
3	D	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC)

Sequence modifications

A, B: 1 - 163 (UniProt: O70274)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

C, D: 315 - 456 (UniProt: Q32NY4)

PDB	External Database	Details
Gly 304	-	expression tag
Pro 305	-	expression tag
Leu 306	-	expression tag
Asn 307	-	expression tag
Met 308	-	expression tag
Ile 309	-	expression tag
Gln 310	-	expression tag
Gly 311	-	expression tag
Val 312	-	expression tag
Leu 313	-	expression tag
Glu 314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	76469.6
Non-Polymers*	Number of molecules	1
	Total formula weight	189.1
All*	Total formula weight	76658.7

*Water molecules are not included.