5K24
Crystal structure of the complex between phosphatase PRL-2 in the oxidized state with the Bateman domain of murine magnesium transporter CNNM3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005768 | cellular_component | endosome |
| A | 0005769 | cellular_component | early endosome |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005768 | cellular_component | endosome |
| B | 0005769 | cellular_component | early endosome |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
| C | 0010960 | biological_process | magnesium ion homeostasis |
| D | 0010960 | biological_process | magnesium ion homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue FLC D 501 |
| Chain | Residue |
| D | LYS404 |
| D | LYS404 |
| D | ASP406 |
| D | ASP406 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP69 | |
| B | ASP69 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160 |
| Chain | Residue | Details |
| A | CYS101 | |
| B | CYS101 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | VAL102 | |
| A | ARG107 | |
| B | VAL102 | |
| B | ARG107 |
