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5K0I

mpges1 bound to an inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Prostaglandin E synthasepolymer15417323.61UniProt (O14684)
Pfam (PF01124)
Homo sapiens (Human)Microsomal glutathione S-transferase 1-like 1,MGST1-L1,Microsomal prostaglandin E synthase 1,MPGES-1,p53-induced gene 12 protein
2B
(A)
1,5-anhydro-2,3,4-trideoxy-3-{[(4S)-3,3-dimethyl-1-(8-methylquinolin-2-yl)piperidine-4-carbonyl]amino}-D-erythro-hexitolnon-polymer411.51Chemie (6PW)
3C
(A)
GLUTATHIONEnon-polymer307.31Chemie (GSH)
4D, E
(A)
octyl beta-D-glucopyranosidenon-polymer292.42Chemie (BOG)
5F, G
(A)
TETRAETHYLENE GLYCOLnon-polymer194.22Chemie (PG4)
6H
(A)
waterwater18.0133Chemie (HOH)
Sequence modifications
A: 2 - 152 (UniProt: O14684)
PDBExternal DatabaseDetails
Met -1-initiating methionine
Ala 0-expression tag
Leu 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17323.6
Non-Polymers*Number of molecules6
Total formula weight1692.0
All*Total formula weight19015.6
*Water molecules are not included.

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PDB entries from 2025-07-09

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