5JXE
Human PD-1 ectodomain complexed with Pembrolizumab Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Programmed cell death protein 1 | polymer | 114 | 12714.1 | 2 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (Human) | hPD-1 |
| 2 | C, E (C, F) | Pembrolizumab Fab light chain | polymer | 218 | 23768.4 | 2 | Homo sapiens | ||
| 3 | D, F (D, G) | Pembrolizumab Fab heavy chain | polymer | 218 | 23681.5 | 2 | Homo sapiens | ||
| 4 | G, H (D, G) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B: 33 - 146 (UniProt: Q15116)
| PDB | External Database | Details |
|---|---|---|
| Ser 93 | Cys 93 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 120328.1 | |
| All* | Total formula weight | 120328.1 |
