5JXE
Human PD-1 ectodomain complexed with Pembrolizumab Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Programmed cell death protein 1 | polymer | 114 | 12714.1 | 2 | UniProt (Q15116) Pfam (PF07686) In PDB | Homo sapiens (Human) | hPD-1 |
2 | C, F | Pembrolizumab Fab light chain | polymer | 218 | 23768.4 | 2 | Homo sapiens | ||
3 | D, G | Pembrolizumab Fab heavy chain | polymer | 218 | 23681.5 | 2 | Homo sapiens | ||
4 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B: 33 - 146 (UniProt: Q15116)
PDB | External Database | Details |
---|---|---|
Ser 93 | Cys 93 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 120328.1 | |
All* | Total formula weight | 120328.1 |