5JXE

Human PD-1 ectodomain complexed with Pembrolizumab Fab

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0050777	biological_process	negative regulation of immune response
B	0016020	cellular_component	membrane
B	0050777	biological_process	negative regulation of immune response

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
C	TYR196-HIS202
D	TYR201-HIS207

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305|PubMed:28165004

Chain	Residue	Details
A	ASN49
A	ASN74
A	ASN116
B	ASN49
B	ASN74
B	ASN116

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28165004, ECO:0007744|PDB:5WT9

Chain	Residue	Details
A	ASN58
B	ASN58

---