5JMN

Fusidic acid bound AcrB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Multidrug efflux pump subunit AcrB	polymer	1057	114736.3	3	UniProt (P31224) Pfam (PF00873)	Escherichia coli (strain K12)	AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B
2	D, E (D, E)	DARPin	polymer	169	18317.6	2		synthetic construct
3	AA, F, O (C, A, B)	FUSIDIC ACID	non-polymer		516.7	3	Chemie (FUA)
4	BA, CA, DA, EA, G... (C, A, B)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	10	Chemie (LMT)
5	FA, J (C, A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	GA, HA, K, RA, S... (C, A, D, B, E)	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
7	L, M, OA (A, C)	2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		208.3	3	Chemie (ETE)
8	N, QA (A, C)	HEXANE	non-polymer		86.2	2	Chemie (HEX)
9	IA, JA, KA, U (C, B)	PHOSPHATIDYLETHANOLAMINE	non-polymer		734.0	4	Chemie (PTY)
10	LA, MA, NA, V (C, B)	DODECANE	non-polymer		170.3	4	Chemie (D12)
11	PA, W (C, B)	N-OCTANE	non-polymer		114.2	2	Chemie (OCT)
12	X (B)	3,6,9,12,15-PENTAOXAHEPTADECANE	non-polymer		250.3	1	Chemie (P3G)
13	Y, Z (B)	DECANE	non-polymer		142.3	2	Chemie (D10)
14	UA, VA, WA, XA, YA (A, B, C, D, E)	water	water		18.0	815	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 1049 (UniProt: P31224)

PDB	External Database	Details
Leu 1050	-	expression tag
Glu 1051	-	expression tag
His 1052	-	expression tag
His 1053	-	expression tag
His 1054	-	expression tag
His 1055	-	expression tag
His 1056	-	expression tag
His 1057	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	380844.0
Non-Polymers*	Number of molecules	41
	Total formula weight	12763.1
All*	Total formula weight	393607.1

*Water molecules are not included.