5JKK
Crystal structure of the negatively supercharged variant Ftn(neg) of human heavy chain ferritin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ferritin heavy chain | polymer | 183 | 21355.5 | 8 | UniProt (P02794) Pfam (PF00210) | Homo sapiens (Human) | Ferritin H subunit,Cell proliferation-inducing gene 15 protein,Negatively charged variant of human heavy chain ferritin |
| 2 | DA, HA, I, J, JA... (F, G, A, H, B...) | FE (III) ION | non-polymer | 55.8 | 10 | Chemie (FE) | |||
| 3 | AA, BA, CA, EA, FA... (E, F, G, A, H...) | MAGNESIUM ION | non-polymer | 24.3 | 17 | Chemie (MG) | |||
| 4 | M, Y (A, D) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | LA, MA, NA, OA, PA... (A, B, C, D, E...) | water | water | 18.0 | 1681 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 0 - 182 (UniProt: P02794)
| PDB | External Database | Details |
|---|---|---|
| Glu 18 | Ala 19 | engineered mutation |
| Gln 86 | Lys 87 | engineered mutation |
| Glu 90 | Cys 91 | engineered mutation |
| Glu 102 | Cys 103 | engineered mutation |
| Glu 105 | His 106 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 170844.4 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 1042.5 | |
| All* | Total formula weight | 171886.9 |
