5JCP

RhoGAP domain of ARAP3 in complex with RhoA in the transition state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA	polymer	419	47132.6	2	UniProt (Q8WWN8) UniProt (P61586) Pfam (PF00620) Pfam (PF00071)	Homo sapiens (Human)
2	C, F (B, A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
3	D, G (B, A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	E, H (B, A)	TETRAFLUOROALUMINATE ION	non-polymer		103.0	2	Chemie (ALF)
5	I, J (B, A)	water	water		18.0	192	Chemie (HOH)

Sequence modifications

B, A: 906 - 1107 (UniProt: Q8WWN8)

PDB	External Database	Details
Met 897	-	expression tag
Gly 898	-	expression tag
His 899	-	expression tag
His 900	-	expression tag
His 901	-	expression tag
His 902	-	expression tag
His 903	-	expression tag
His 904	-	expression tag
Met 905	-	expression tag

B, A: 1108 - 1135 (PDB: 5JCP)
B, A: 2 - 181 (UniProt: P61586)

PDB	External Database	Details
Asn 25	Phe 25	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94265.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1141.0
All*	Total formula weight	95406.2

*Water molecules are not included.