5JA3
Mycobacterium tuberculosis Dihydrofolate Reductase complexed with beta- NADPH and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-b iphenyl]-4-carboxylic acid (UCP1106)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Dihydrofolate reductase | polymer | 159 | 17661.0 | 4 | UniProt (P9WNX0) Pfam (PF00186) UniProt (by SIFTS) (P9WNX1) In PDB | Mycobacterium tuberculosis | |
2 | A, B, C, D | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) | |||
3 | A, B, C, D | 4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-4-methoxy-phenyl]benzoic acid | non-polymer | 402.4 | 4 | Chemie (U06) | |||
4 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 70644.0 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 4591.5 | |
All* | Total formula weight | 75235.4 |