5J7L
Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AA, BA | 16S rRNA | polymer | 1534 | 497444.0 | 2 | GenBank (595593103) | Escherichia coli (strain K12) | |
2 | AB, BB | 30S ribosomal protein S2 | polymer | 224 | 24971.8 | 2 | UniProt (P0A7V0) Pfam (PF00318) In PDB | Escherichia coli (strain K12) | |
3 | AC, BC | 30S ribosomal protein S3 | polymer | 206 | 23078.8 | 2 | UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189) In PDB | Escherichia coli (strain K12) | |
4 | AD, BD | 30S ribosomal protein S4 | polymer | 205 | 23383.0 | 2 | UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479) In PDB | Escherichia coli (strain K12) | |
5 | AE, BE | 30S ribosomal protein S5 | polymer | 155 | 16361.9 | 2 | UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719) In PDB | Escherichia coli (strain K12) | |
6 | AF, BF | 30S ribosomal protein S6 | polymer | 106 | 12326.3 | 2 | UniProt (P02358) Pfam (PF01250) In PDB | Escherichia coli (strain K12) | |
7 | AG, BG | 30S ribosomal protein S7 | polymer | 151 | 16861.5 | 2 | UniProt (P02359) Pfam (PF00177) In PDB | Escherichia coli (strain K12) | |
8 | AH, BH | 30S ribosomal protein S8 | polymer | 129 | 14015.4 | 2 | UniProt (P0A7W7) Pfam (PF00410) In PDB | Escherichia coli (strain K12) | |
9 | AI, BI | 30S ribosomal protein S9 | polymer | 127 | 14554.9 | 2 | UniProt (P0A7X3) Pfam (PF00380) In PDB | Escherichia coli (strain K12) | |
10 | AJ, BJ | 30S ribosomal protein S10 | polymer | 99 | 11325.1 | 2 | UniProt (P0A7R5) Pfam (PF00338) In PDB | Escherichia coli (strain K12) | |
11 | AK, BK | 30S ribosomal protein S11 | polymer | 117 | 12487.2 | 2 | UniProt (P0A7R9) Pfam (PF00411) In PDB | Escherichia coli (strain K12) | |
12 | AL, BL | 30S ribosomal protein S12 | polymer | 123 | 13683.1 | 2 | UniProt (P0A7S3) Pfam (PF00164) In PDB | Escherichia coli (strain K12) | |
13 | AM, BM | 30S ribosomal protein S13 | polymer | 114 | 12625.8 | 2 | UniProt (P0A7S9) Pfam (PF00416) In PDB | Escherichia coli (strain K12) | |
14 | AN, BN | 30S ribosomal protein S14 | polymer | 100 | 11475.4 | 2 | UniProt (P0AG59) Pfam (PF00253) In PDB | Escherichia coli (strain K12) | |
15 | AO, BO | 30S ribosomal protein S15 | polymer | 88 | 10159.6 | 2 | UniProt (P0ADZ4) Pfam (PF00312) In PDB | Escherichia coli (strain K12) | |
16 | AP, BP | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 2 | UniProt (P0A7T3) Pfam (PF00886) In PDB | Escherichia coli (strain K12) | |
17 | AQ, BQ | 30S ribosomal protein S17 | polymer | 80 | 9263.9 | 2 | UniProt (P0AG63) Pfam (PF00366) In PDB | Escherichia coli (strain K12) | |
18 | AR, BR | 30S ribosomal protein S18 | polymer | 55 | 6466.5 | 2 | UniProt (P0A7T7) Pfam (PF01084) In PDB | Escherichia coli (strain K12) | |
19 | AS, BS | 30S ribosomal protein S19 | polymer | 79 | 9057.6 | 2 | UniProt (P0A7U3) Pfam (PF00203) In PDB | Escherichia coli (strain K12) | |
20 | AT, BT | 30S ribosomal protein S20 | polymer | 86 | 9577.3 | 2 | UniProt (P0A7U7) Pfam (PF01649) In PDB | Escherichia coli (strain K12) | |
21 | AU, BU | 30S ribosomal protein S21 | polymer | 56 | 6629.7 | 2 | UniProt (P68679) Pfam (PF01165) In PDB | Escherichia coli (strain K12) | |
22 | C1, D1 | 50S ribosomal protein L32 | polymer | 56 | 6332.2 | 2 | UniProt (P0A7N4) Pfam (PF01783) In PDB | Escherichia coli (strain K12) | |
23 | C2, D2 | 50S ribosomal protein L33 | polymer | 51 | 5928.0 | 2 | UniProt (P0A7N9) Pfam (PF00471) In PDB | Escherichia coli (strain K12) | |
24 | C3, D3 | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 2 | UniProt (P0A7P5) Pfam (PF00468) In PDB | Escherichia coli (strain K12) | |
25 | C4, D4 | 50S ribosomal protein L35 | polymer | 64 | 7181.8 | 2 | UniProt (P0A7Q1) Pfam (PF01632) In PDB | Escherichia coli (strain K12) | Ribosomal protein A |
26 | C5, D5 | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 2 | UniProt (P0A7Q6) Pfam (PF00444) In PDB | Escherichia coli (strain K12) | Ribosomal protein B |
27 | C0, D0 | 50S ribosomal protein L30 | polymer | 58 | 6423.6 | 2 | UniProt (P0AG51) Pfam (PF00327) In PDB | Escherichia coli (strain K12) | |
28 | CB, DB | 5S rRNA | polymer | 120 | 38790.1 | 2 | GenBank (923416119) | Escherichia coli (strain K12) | |
29 | CC, DC | 50S ribosomal protein L2 | polymer | 271 | 29663.2 | 2 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) In PDB | Escherichia coli (strain K12) | |
30 | CD, DD | 50S ribosomal protein L3 | polymer | 209 | 22291.6 | 2 | UniProt (P60438) Pfam (PF00297) In PDB | Escherichia coli (strain K12) | |
31 | CA | 23S rRNA | polymer | 2904 | 941809.6 | 1 | GenBank (802133627) | Escherichia coli (strain K12) | |
32 | CE, DE | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 2 | UniProt (P60723) Pfam (PF00573) In PDB | Escherichia coli (strain K12) | |
33 | CF, DF | 50S ribosomal protein L5 | polymer | 177 | 20073.2 | 2 | UniProt (P62399) Pfam (PF00281) Pfam (PF00673) In PDB | Escherichia coli (strain K12) | |
34 | CG, DG | 50S ribosomal protein L6 | polymer | 176 | 18801.6 | 2 | UniProt (P0AG55) Pfam (PF00347) In PDB | Escherichia coli (strain K12) | |
35 | CH, DH | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 2 | UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948) In PDB | Escherichia coli (strain K12) | |
36 | CJ, DJ | 50S ribosomal protein L11 | polymer | 134 | 14020.3 | 2 | UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298) In PDB | Escherichia coli (strain K12) | |
37 | CK, DK | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 2 | UniProt (P0AA10) Pfam (PF00572) In PDB | Escherichia coli (strain K12) | |
38 | CL, DL | 50S ribosomal protein L14 | polymer | 123 | 13565.1 | 2 | UniProt (P0ADY3) Pfam (PF00238) In PDB | Escherichia coli (strain K12) | |
39 | CM, DM | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 2 | UniProt (P02413) Pfam (PF00828) In PDB | Escherichia coli (strain K12) | |
40 | CN, DN | 50S ribosomal protein L16 | polymer | 136 | 15327.3 | 2 | UniProt (P0ADY7) Pfam (PF00252) In PDB | Escherichia coli (strain K12) | |
41 | CO, DO | 50S ribosomal protein L17 | polymer | 125 | 14193.5 | 2 | UniProt (P0AG44) Pfam (PF01196) In PDB | Escherichia coli (strain K12) | |
42 | CP, DP | 50S ribosomal protein L18 | polymer | 117 | 12794.7 | 2 | UniProt (P0C018) Pfam (PF00861) In PDB | Escherichia coli (strain K12) | |
43 | CQ, DQ | 50S ribosomal protein L19 | polymer | 114 | 13028.1 | 2 | UniProt (P0A7K6) Pfam (PF01245) In PDB | Escherichia coli (strain K12) | |
44 | CR, DR | 50S ribosomal protein L20 | polymer | 117 | 13396.8 | 2 | UniProt (P0A7L3) Pfam (PF00453) In PDB | Escherichia coli (strain K12) | |
45 | CS, DS | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 2 | UniProt (P0AG48) Pfam (PF00829) In PDB | Escherichia coli (strain K12) | |
46 | CT, DT | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 2 | UniProt (P61175) Pfam (PF00237) In PDB | Escherichia coli (strain K12) | |
47 | CU, DU | 50S ribosomal protein L23 | polymer | 93 | 10546.5 | 2 | UniProt (P0ADZ0) Pfam (PF00276) In PDB | Escherichia coli (strain K12) | |
48 | CV, DV | 50S ribosomal protein L24 | polymer | 102 | 11078.9 | 2 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) In PDB | Escherichia coli (strain K12) | |
49 | CW, DW | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 2 | UniProt (P68919) Pfam (PF01386) In PDB | Escherichia coli (strain K12) | |
50 | CX, DX | 50S ribosomal protein L27 | polymer | 76 | 8275.5 | 2 | UniProt (P0A7L8) Pfam (PF01016) In PDB | Escherichia coli (strain K12) | |
51 | CY, DY | 50S ribosomal protein L28 | polymer | 77 | 8896.4 | 2 | UniProt (P0A7M2) Pfam (PF00830) In PDB | Escherichia coli (strain K12) | |
52 | CZ, DZ | 50S ribosomal protein L29 | polymer | 62 | 7155.3 | 2 | UniProt (P0A7M6) Pfam (PF00831) In PDB | Escherichia coli (strain K12) | |
53 | DI | 50S ribosomal protein L10 | polymer | 135 | 14568.7 | 1 | UniProt (P0A7J3) Pfam (PF00466) In PDB | Escherichia coli (strain K12) | 50S ribosomal protein L8 |
54 | DA | 23S rRNA | polymer | 2904 | 941811.6 | 1 | GenBank (802133627) | Escherichia coli (strain K12) | |
55 | AA, BA, CA, DA, DB... | MAGNESIUM ION | non-polymer | 24.3 | 472 | Chemie (MG) | |||
56 | DS, DA, AA, DQ, BA... | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 7 | Chemie (PG4) | |||
57 | DA, DS, DT, DE, DK... | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 14 | Chemie (MPD) | |||
58 | DA, DM, AA | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 16 | Chemie (PUT) | |||
59 | AA, BA | TETRACYCLINE | non-polymer | 444.4 | 4 | Chemie (TAC) | |||
60 | AB, C5, D5 | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
61 | DA, AL, D1, D3, DL... | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 11 | Chemie (PEG) | |||
62 | DA, D1, DB | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
63 | D1, DU, DA, DS | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 9 | Chemie (PGE) | |||
64 | DA | SPERMIDINE | non-polymer | 145.2 | 4 | Chemie (SPD) | |||
65 | DA | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
66 | DA | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
67 | DA | GUANINE | non-polymer | 151.1 | 1 | Chemie (GUN) | |||
68 | DA | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
69 | water | water | 18.0 | 7744 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 1534 (GenBank: 595593103)
DI: 2 - 136 (UniProt: P0A7J3)
PDB | External Database | Details |
---|---|---|
G 1052 | U 4719137 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Val 85 | Ser 85 | conflict |
Thr 86 | Met 86 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 105 |
Total formula weight | 4250224.8 | |
Non-Polymers* | Number of molecules | 559 |
Total formula weight | 22645.0 | |
All* | Total formula weight | 4272869.8 |