5J0A

Crystal structure of PDZ-binding kinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Lymphokine-activated killer T-cell-originated protein kinase	polymer	300	33629.0	1	UniProt (Q96KB5) Pfam (PF00069) In PDB	Homo sapiens (Human)	Cancer/testis antigen 84,CT84,MAPKK-like protein kinase,Nori-3,PDZ-binding kinase,Spermatogenesis-related protein kinase,SPK,T-LAK cell-originated protein kinase
2	B	Lymphokine-activated killer T-cell-originated protein kinase	polymer	304	34001.5	1	UniProt (Q96KB5) Pfam (PF00069) In PDB	Homo sapiens (Human)	Cancer/testis antigen 84,CT84,MAPKK-like protein kinase,Nori-3,PDZ-binding kinase,Spermatogenesis-related protein kinase,SPK,T-LAK cell-originated protein kinase
3	A, B	SULFATE ION	non-polymer		96.1	10	Chemie (SO4)
4	A, B	4'-HYDROXYCINNAMIC ACID	non-polymer		164.2	4	Chemie (HC4)
5		water	water		18.0	142	Chemie (HOH)

Sequence modifications

A: 23 - 320 (UniProt: Q96KB5)

PDB	External Database	Details
Gly 22	-	expression tag
Glu 198	Thr 198	engineered mutation
Ala 321	-	expression tag

B: 19 - 319 (UniProt: Q96KB5)

PDB	External Database	Details
Gly 18	-	expression tag
Glu 198	Thr 198	engineered mutation
Ala 320	-	expression tag
Ala 321	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67630.5
Non-Polymers*	Number of molecules	14
	Total formula weight	1617.3
All*	Total formula weight	69247.8

*Water molecules are not included.