5IPZ
Crystal structure of human carbonic anhydrase isozyme IV with 5-(2-amino-1,3-thiazol-4-yl)-2-chlorobenzenesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 4 | polymer | 267 | 30495.7 | 4 | UniProt (P22748) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase IV,Carbonic anhydrase IV,CA-IV |
| 2 | E, G, I, K (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, H, J (A, B, C) | 5-(2-amino-1,3-thiazol-4-yl)-2-chlorobenzene-1-sulfonamide | non-polymer | 289.8 | 3 | Chemie (6CC) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 267 (UniProt: P22748)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 121982.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1130.9 | |
| All* | Total formula weight | 123113.6 |
