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5IL0

Crystal structural of the METTL3-METTL14 complex for N6-adenosine methylation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
METTL3polymer21224427.11UniProt (Q86U44)
Pfam (PF05063)
Homo sapiens (Human)MT-A70,Methyltransferase-like protein 3
2B
(B)
METTL14polymer30034794.41UniProt (Q9HCE5)
Pfam (PF05063)
Homo sapiens (Human)Methyltransferase-like protein 14
3C, D
(A, B)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
4E
(B)
BROMIDE IONnon-polymer79.91Chemie (BR)
5F, G
(A, B)
waterwater18.0331Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59221.5
Non-Polymers*Number of molecules3
Total formula weight204.0
All*Total formula weight59425.6
*Water molecules are not included.

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PDB entries from 2025-07-30

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