5II1
Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with 1-methylisochromeno[3,4-c]pyrazol-5(3H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein polybromo-1 | polymer | 124 | 14648.0 | 2 | UniProt (Q86U86) Pfam (PF00439) | Homo sapiens (Human) | hPB1,BRG1-associated factor 180,BAF180,Polybromo-1D |
| 2 | C, D (A, B) | 1-methyl[2]benzopyrano[3,4-c]pyrazol-5(3H)-one | non-polymer | 200.2 | 2 | Chemie (6BL) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A, B: 645 - 766 (UniProt: Q86U86)
| PDB | External Database | Details |
|---|---|---|
| Ser 643 | - | expression tag |
| Met 644 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29296.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 400.4 | |
| All* | Total formula weight | 29696.4 |
