5IFS
Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tether containing UBX domain for GLUT4 | polymer | 237 | 26451.4 | 2 | UniProt (Q9BZE9) Pfam (PF00789) | Homo sapiens (Human) | Alveolar soft part sarcoma chromosomal region candidate gene 1 protein,Alveolar soft part sarcoma locus,Renal papillary cell carcinoma protein 17,UBX domain-containing protein 9 |
| 2 | B, D (B, D) | Transitional endoplasmic reticulum ATPase | polymer | 481 | 53508.2 | 2 | UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) | Homo sapiens (Human) | TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP |
| 3 | E, K (B, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | F, L (B, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | H, I, M (B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | J (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 159919.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1277.4 | |
| All* | Total formula weight | 161196.4 |
