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5IES

Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.16 A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
VRC01cHuGL2 Fab heavy chainpolymer22123614.51Homo sapiens (Human)
2B
(L)
VRC01cHuGL2 Fab light chainpolymer21623816.41Homo sapiens (Human)
3C
(C)
Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8polymer18319889.31Homo sapiens (Human)
4D, E, F
(H, L)
GLYCEROLnon-polymer92.13Chemie (GOL)
5G, H
(C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
6I, J, K
(H, L, C)
waterwater18.0187Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight67320.2
Non-Polymers*Number of molecules5
Total formula weight718.7
All*Total formula weight68038.9
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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