5IC1

Structural analysis of a talin triple domain module, E1794Y, E1797Y, Q1801Y mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Talin-1	polymer	469	49406.6	1	UniProt (P26039) Pfam (PF21865) In PDB	Mus musculus (Mouse)
2	A	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
3		water	water		18.0	135	Chemie (HOH)

Sequence modifications

A: 1357 - 1822 (UniProt: P26039)

PDB	External Database	Details
Gly 1354	-	expression tag
His 1355	-	expression tag
Met 1356	-	expression tag
Tyr 1794	Glu 1794	engineered mutation
Tyr 1797	Glu 1797	engineered mutation
Tyr 1801	Gln 1801	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	49406.6
Non-Polymers*	Number of molecules	3
	Total formula weight	186.2
All*	Total formula weight	49592.8

*Water molecules are not included.