5I4Z

Structure of apo OmoMYC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Myc proto-oncogene protein	polymer	118	14036.0	2	UniProt (P01106) Pfam (PF00010) Pfam (PF02344)	Homo sapiens (Human)	OmoMYC,Class E basic helix-loop-helix protein 39,bHLHe39,Proto-oncogene c-Myc,Transcription factor p64
2	C, D, G (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
3	E, F, H (A, B)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
4	I, J (B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
5	K, L (A, B)	water	water		18.0	114	Chemie (HOH)

Sequence modifications

A, B: 1 - 92 (UniProt: P01106)

PDB	External Database	Details
Met -25	-	initiating methionine
Lys -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Pro -17	-	expression tag
Met -16	-	expression tag
Ser -15	-	expression tag
Asp -14	-	expression tag
Tyr -13	-	expression tag
Asp -12	-	expression tag
Ile -11	-	expression tag
Pro -10	-	expression tag
Thr -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ala 0	-	expression tag
Met 1	Ser 348	conflict
Ala 2	Asp 349	conflict
Thr 63	Glu 410	engineered mutation
Ile 70	Glu 417	engineered mutation
Gln 76	Arg 423	engineered mutation
Asn 77	Arg 424	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28072.1
Non-Polymers*	Number of molecules	8
	Total formula weight	460.8
All*	Total formula weight	28532.9

*Water molecules are not included.