5I35
Structure of the Human mitochondrial kinase COQ8A R611K with AMPPNP (Cerebellar Ataxia and Ubiquinone Deficiency Through Loss of Unorthodox Kinase Activity)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Atypical kinase ADCK3, mitochondrial | polymer | 393 | 45923.4 | 1 | UniProt (Q8NI60) Pfam (PF03109) | Homo sapiens (Human) | Chaperone activity of bc1 complex-like,Chaperone-ABC1-like,aarF domain-containing protein kinase 3 |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 256 - 647 (UniProt: Q8NI60)
| PDB | External Database | Details |
|---|---|---|
| Ser 255 | - | expression tag |
| Lys 611 | Arg 611 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45923.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 506.2 | |
| All* | Total formula weight | 46429.6 |
