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5I35

Structure of the Human mitochondrial kinase COQ8A R611K with AMPPNP (Cerebellar Ataxia and Ubiquinone Deficiency Through Loss of Unorthodox Kinase Activity)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005739cellular_componentmitochondrion
A0006744biological_processubiquinone biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues12
Detailsbinding site for residue ANP A 700
ChainResidue
APHE336
AASN493
APHE495
AASP507
AALA337
AALA339
ASER340
AVAL344
ALYS358
ATHR445
AGLU446
AVAL448

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000305|PubMed:27499294
ChainResidueDetails
AASP488

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27499294, ECO:0000305|PubMed:25498144, ECO:0000312|PDB:5I35
ChainResidueDetails
ASER340

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27499294, ECO:0000312|PDB:5I35
ChainResidueDetails
ALYS358
ATHR445
AASN493
AASP507

229183

PDB entries from 2024-12-18

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