5I35
Structure of the Human mitochondrial kinase COQ8A R611K with AMPPNP (Cerebellar Ataxia and Ubiquinone Deficiency Through Loss of Unorthodox Kinase Activity)
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue ANP A 700 |
| Chain | Residue |
| A | PHE336 |
| A | ASN493 |
| A | PHE495 |
| A | ASP507 |
| A | ALA337 |
| A | ALA339 |
| A | SER340 |
| A | VAL344 |
| A | LYS358 |
| A | THR445 |
| A | GLU446 |
| A | VAL448 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Motif: {"description":"KxGQ motif","evidences":[{"source":"PubMed","id":"25498144","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"AAAS motif","evidences":[{"source":"PubMed","id":"25498144","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"27499294","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27499294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25498144","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5I35","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27499294","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5I35","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
