5HVT
Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Macrophage migration inhibitory factor | polymer | 114 | 12355.1 | 3 | UniProt (P14174) Pfam (PF01187) In PDB | Homo sapiens (Human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
2 | A, B, C | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
3 | A, B, C | 7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one | non-polymer | 271.3 | 3 | Chemie (NVS) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | A, B, C | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 3 | Chemie (IPA) | |||
6 | water | water | 18.0 | 284 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 37065.2 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 1846.7 | |
All* | Total formula weight | 38911.9 |