5HS3
Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... (A, B, C, D, E...) | Thymidylate synthase | polymer | 289 | 33167.0 | 6 | UniProt (P04818) Pfam (PF00303) | Homo sapiens (Human) | TSase |
2 | G, I, K, L, M... (A, B, C, D, E...) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 6 | Chemie (UMP) | |||
3 | H, J, N (A, B, E) | 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol | non-polymer | 284.3 | 3 | Chemie (KI3) | |||
4 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 26 - 313 (UniProt: P04818)
PDB | External Database | Details |
---|---|---|
Met 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 199002.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 2702.1 | |
All* | Total formula weight | 201704.4 |