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5HS3

Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Thymidylate synthasepolymer28933167.06UniProt (P04818)
Pfam (PF00303)
Homo sapiens (Human)TSase
2G, I, K, L, M...
(A, B, C, D, E...)
2'-DEOXYURIDINE 5'-MONOPHOSPHATEnon-polymer308.26Chemie (UMP)
3H, J, N
(A, B, E)
3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-olnon-polymer284.33Chemie (KI3)
4P, Q, R, S
(A, B, C, D)
waterwater18.011Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 26 - 313 (UniProt: P04818)
PDBExternal DatabaseDetails
Met 25-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight199002.3
Non-Polymers*Number of molecules9
Total formula weight2702.1
All*Total formula weight201704.4
*Water molecules are not included.

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PDB entries from 2024-11-20

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