5HPE
Phosphatase domain of PP5 bound to a phosphomimetic Cdc37 substrate peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein phosphatase 5,Hsp90 co-chaperone Cdc37 | polymer | 350 | 39768.8 | 1 | UniProt (P53041) UniProt (K7EJ06) Pfam (PF08321) Pfam (PF00149) UniProt (by SIFTS) (Q16543) | Homo sapiens (Human) | PP5,Protein phosphatase T,PPT |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, E (A) | COBALT HEXAMMINE(III) | non-polymer | 161.1 | 2 | Chemie (NCO) | |||
| 4 | F (A) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 175 - 499 (UniProt: P53041)
A: 509 - 1020 (UniProt: K7EJ06)
| PDB | External Database | Details |
|---|---|---|
| Gly 500 | - | linker |
| Ser 501 | - | linker |
| Gly 502 | - | linker |
| Ser 503 | - | linker |
| Gly 504 | - | linker |
| Ser 505 | - | linker |
| Ala 506 | - | linker |
| Ser 507 | - | linker |
| Arg 508 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 1013 | Ser 13 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39768.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 432.1 | |
| All* | Total formula weight | 40200.9 |
