5HJQ

Crystal structure of the TBC domain of Skywalker/TBC1D24 from Drosophila melanogaster in complex with inositol(1,4,5)triphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	LD10117p	polymer	376	43096.8	1	UniProt (Q9VIH7) Pfam (PF00566)	Drosophila melanogaster (Fruit fly)	Skywalker,isoform A,isoform B,isoform H
2	B (A)	D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE	non-polymer		420.1	1	Chemie (I3P)
3	C (A)	water	water		18.0	30	Chemie (HOH)

Sequence modifications

A: 1 - 353 (UniProt: Q9VIH7)

PDB	External Database	Details
Met -22	-	initiating methionine
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43096.8
Non-Polymers*	Number of molecules	1
	Total formula weight	420.1
All*	Total formula weight	43516.9

*Water molecules are not included.