5HJ3

Crystal structure of host-primed Ebola virus GP, GPcl.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I, M (C, G, K, O)	Envelope glycoprotein	polymer	179	19604.2	4	UniProt (Q05320) Pfam (PF01611)	Ebola virus sp.	GP1,2,GP
2	B, F, J, N (D, H, L, P)	Envelope glycoprotein	polymer	136	15335.4	4	UniProt (P87666) Pfam (PF22307)	Zaire ebolavirus (ZEBOV)	GP1,2,GP
3	C, G, K, O (E, I, M, A)	KZ52 Antibody Fragment	polymer	226	24021.0	4		Homo sapiens (Human)
4	D, H, L, P (F, J, N, B)	KZ52 Antibody Fragment	polymer	217	23896.6	4		Homo sapiens (Human)
5	Q, R, S, T (Q, R, S, T)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	4	In PDB GlyTouCan (G23799GS)

Sequence modifications

C, G, K, O: 32 - 194 (UniProt: Q05320)

PDB	External Database	Details
Tyr 16	-	expression tag
Pro 17	-	expression tag
Tyr 18	-	expression tag
Asp 19	-	expression tag
Val 20	-	expression tag
Pro 21	-	expression tag
Asp 22	-	expression tag
Tyr 23	-	expression tag
Ala 24	-	expression tag
Ile 25	-	expression tag
Glu 26	-	expression tag
Gly 27	-	expression tag
Arg 28	-	expression tag
Gly 29	-	expression tag
Ala 30	-	expression tag
Arg 31	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	331428.3
Branched	Number of molecules	4
	Total formula weight	4940.4
All*	Total formula weight	336368.7

*Water molecules are not included.