5HFM
Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Envelope glycoprotein gp160,gp41 CHR region | polymer | 82 | 9446.8 | 6 | UniProt (Q70626) Pfam (PF00517) UniProt (by SIFTS) (P04578) In PDB | Human immunodeficiency virus 1 (HIV-1) | Env polyprotein |
2 | B, F | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 2 | Chemie (TAM) | |||
3 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 539 - 581 (UniProt: Q70626)
A, B, C, D, E, F: 622 - 656 (PDB: 5HFM)
PDB | External Database | Details |
---|---|---|
Gly 535 | - | expression tag |
Pro 536 | - | expression tag |
Met 537 | - | expression tag |
Ala 538 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 56681.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 326.4 | |
All* | Total formula weight | 57007.5 |