5HFM
Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | ROTATING ANODE |
Source details | RIGAKU MICROMAX-007 |
Temperature [K] | 100 |
Detector technology | IMAGE PLATE |
Collection date | 2015-08-06 |
Detector | RIGAKU RAXIS IV |
Wavelength(s) | 1.5418 |
Spacegroup name | P 1 |
Unit cell lengths | 39.112, 39.076, 90.602 |
Unit cell angles | 90.03, 89.98, 120.06 |
Refinement procedure
Resolution | 33.850 - 2.298 |
R-factor | 0.2029 |
Rwork | 0.200 |
R-free | 0.24670 |
RMSD bond length | 0.003 |
RMSD bond angle | 0.497 |
Data reduction software | HKL-2000 |
Data scaling software | HKL-2000 |
Phasing software | PHASER |
Refinement software | PHENIX (1.8.2_1309) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 33.900 |
High resolution limit [Å] | 2.298 |
Number of reflections | 18969 |
<I/σ(I)> | 16.4 |
Completeness [%] | 92.3 |
Redundancy | 1.6 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION | 8.2 | 289 | 1.4 M Sodium Potassium Phosphate |