5H4J
Crystal structure of Human dUTPase in complex with N-[(1R)-1-[3-(Cyclopentyloxy)-phenyl]-ethyl]-3-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methoxy]-1-propanesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | polymer | 164 | 17771.1 | 1 | UniProt (P33316) Pfam (PF00692) In PDB | Homo sapiens (Human) | dUTPase,dUTP pyrophosphatase |
| 2 | A | N-[(1R)-1-[3-(Cyclopentyloxy)-phenyl]-ethyl]-3-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methoxy]-1-propanesulfonamide | non-polymer | 451.5 | 1 | Chemie (FKM) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17771.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 664.2 | |
| All* | Total formula weight | 18435.2 |
