5H3E
Crystal structure of mouse isocitrate dehydrogenases 2 K256Q mutant complexed with isocitrate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Isocitrate dehydrogenase [NADP], mitochondrial | polymer | 422 | 47890.5 | 2 | UniProt (P54071) Pfam (PF00180) In PDB | Mus musculus (Mouse) | Isocitrate dehydrogenase 2 |
2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
3 | A, B | ISOCITRIC ACID | non-polymer | 192.1 | 2 | Chemie (ICT) | |||
4 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, B: 40 - 452 (UniProt: P54071)
PDB | External Database | Details |
---|---|---|
Met 39 | - | expression tag |
Gln 256 | Lys 256 | engineered mutation |
Leu 453 | - | expression tag |
Glu 454 | - | expression tag |
His 455 | - | expression tag |
His 456 | - | expression tag |
His 457 | - | expression tag |
His 458 | - | expression tag |
His 459 | - | expression tag |
His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 95781.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 432.9 | |
All* | Total formula weight | 96213.8 |