5GXO

Discovery of a compound that activates SIRT3 to deacetylate Manganese Superoxide Dismutase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Superoxide dismutase [Mn], mitochondrial	polymer	198	22274.1	2	UniProt (P04179) Pfam (PF00081) Pfam (PF02777) In PDB	Homo sapiens (Human)
2	A, B	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3		water	water		18.0	141	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44548.3
Non-Polymers*	Number of molecules	2
	Total formula weight	109.9
All*	Total formula weight	44658.2

*Water molecules are not included.