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5GXO

Discovery of a compound that activates SIRT3 to deacetylate Manganese Superoxide Dismutase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Superoxide dismutase [Mn], mitochondrialpolymer19822274.12UniProt (P04179)
Pfam (PF00081)
Pfam (PF02777)
Homo sapiens (Human)
2C, D
(A, B)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
3E, F
(A, B)
waterwater18.0141Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight44548.3
Non-Polymers*Number of molecules2
Total formula weight109.9
All*Total formula weight44658.2
*Water molecules are not included.

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PDB entries from 2025-10-08

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