5GWZ
The structure of Porcine epidemic diarrhea virus main protease in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | PEDV main protease | polymer | 307 | 33166.5 | 2 | UniProt (P0C6V6) Pfam (PF05409) | Porcine epidemic diarrhea virus CV777 (PEDV) | Peptidase C30 |
| 2 | C, D (D, E) | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | polymer | 6 | 680.8 | 2 | BIRD (PRD_002214) | synthetic construct | |
| 3 | E, F, G (B, A, D) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 302 (UniProt: P0C6V6)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67694.6 | |
| All* | Total formula weight | 67694.6 |
