5GUL

Crystal structure of Tris/PPix2/Mg2+ bound form of cyclolavandulyl diphosphate synthase (CLDS) from Streptomyces sp. CL190

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cyclolavandulyl diphosphate synthase	polymer	238	26676.1	4	UniProt (X5IYJ5)	Streptomyces sp. (strain CL190)
2	E, F, I, J, M... (A, B, C, D)	PYROPHOSPHATE 2-	non-polymer		176.0	8	Chemie (POP)
3	G, K, O, S (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	H, L, P, T (A, B, C, D)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	4	Chemie (TRS)
5	U, V, W, X (A, B, C, D)	water	water		18.0	276	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 217 (UniProt: X5IYJ5)

PDB	External Database	Details
Met -20	-	initiating methionine
Lys -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Leu -8	-	expression tag
Val -7	-	expression tag
Pro -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	106704.5
Non-Polymers*	Number of molecules	16
	Total formula weight	1993.5
All*	Total formula weight	108698.0

*Water molecules are not included.