5GUL
Crystal structure of Tris/PPix2/Mg2+ bound form of cyclolavandulyl diphosphate synthase (CLDS) from Streptomyces sp. CL190
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016094 | biological_process | polyprenol biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0045547 | molecular_function | ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0016094 | biological_process | polyprenol biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0045547 | molecular_function | ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0016094 | biological_process | polyprenol biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0045547 | molecular_function | ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0016094 | biological_process | polyprenol biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0045547 | molecular_function | ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue POP A 301 |
| Chain | Residue |
| A | ASP9 |
| A | TRS304 |
| A | HOH401 |
| A | HOH406 |
| A | HOH411 |
| A | HOH421 |
| B | TYR180 |
| B | ARG211 |
| B | PHE212 |
| B | GLY213 |
| B | HOH425 |
| A | ASN57 |
| A | ARG60 |
| A | ARG163 |
| A | ARG169 |
| A | SER171 |
| A | PHE173 |
| A | POP302 |
| A | MG303 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue POP A 302 |
| Chain | Residue |
| A | ASP9 |
| A | GLY10 |
| A | MET11 |
| A | ARG12 |
| A | ARG13 |
| A | TYR26 |
| A | ARG60 |
| A | POP301 |
| A | MG303 |
| A | TRS304 |
| A | HOH421 |
| B | TYR215 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | ASP9 |
| A | POP301 |
| A | POP302 |
| A | HOH401 |
| A | HOH421 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue TRS A 304 |
| Chain | Residue |
| A | PRO8 |
| A | ASP9 |
| A | MET11 |
| A | TYR26 |
| A | THR51 |
| A | ALA52 |
| A | ASN57 |
| A | PHE68 |
| A | PHE72 |
| A | POP301 |
| A | POP302 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue POP B 301 |
| Chain | Residue |
| A | TYR180 |
| A | ARG211 |
| A | PHE212 |
| A | GLY213 |
| A | HOH412 |
| B | ASP9 |
| B | ASN57 |
| B | ARG60 |
| B | ARG163 |
| B | ARG169 |
| B | SER171 |
| B | PHE173 |
| B | POP302 |
| B | MG303 |
| B | TRS304 |
| B | HOH406 |
| B | HOH408 |
| B | HOH418 |
| B | HOH419 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue POP B 302 |
| Chain | Residue |
| A | TYR215 |
| B | ASP9 |
| B | GLY10 |
| B | MET11 |
| B | ARG12 |
| B | ARG13 |
| B | TYR26 |
| B | ARG60 |
| B | POP301 |
| B | MG303 |
| B | TRS304 |
| B | HOH406 |
| B | HOH419 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 303 |
| Chain | Residue |
| B | ASP9 |
| B | POP301 |
| B | POP302 |
| B | HOH406 |
| B | HOH419 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue TRS B 304 |
| Chain | Residue |
| B | PRO8 |
| B | ASP9 |
| B | MET11 |
| B | TYR26 |
| B | THR51 |
| B | ALA52 |
| B | ASN57 |
| B | PHE68 |
| B | PHE72 |
| B | POP301 |
| B | POP302 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | binding site for residue POP C 301 |
| Chain | Residue |
| C | ARG13 |
| C | TYR26 |
| C | ARG60 |
| C | POP302 |
| C | MG303 |
| C | TRS304 |
| C | HOH402 |
| C | HOH416 |
| D | TYR215 |
| C | ASP9 |
| C | GLY10 |
| C | MET11 |
| C | ARG12 |
| site_id | AD1 |
| Number of Residues | 18 |
| Details | binding site for residue POP C 302 |
| Chain | Residue |
| C | ASP9 |
| C | ASN57 |
| C | ARG60 |
| C | ARG163 |
| C | ARG169 |
| C | SER171 |
| C | POP301 |
| C | MG303 |
| C | TRS304 |
| C | HOH402 |
| C | HOH405 |
| C | HOH408 |
| C | HOH416 |
| D | TYR180 |
| D | ARG211 |
| D | PHE212 |
| D | GLY213 |
| D | HOH406 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 303 |
| Chain | Residue |
| C | ASP9 |
| C | POP301 |
| C | POP302 |
| C | HOH402 |
| C | HOH416 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue TRS C 304 |
| Chain | Residue |
| C | PRO8 |
| C | ASP9 |
| C | TYR26 |
| C | THR51 |
| C | ALA52 |
| C | ASN57 |
| C | PHE68 |
| C | PHE72 |
| C | POP301 |
| C | POP302 |
| site_id | AD4 |
| Number of Residues | 13 |
| Details | binding site for residue POP D 301 |
| Chain | Residue |
| C | TYR215 |
| C | HOH413 |
| D | ASP9 |
| D | GLY10 |
| D | MET11 |
| D | ARG12 |
| D | ARG13 |
| D | TYR26 |
| D | ARG60 |
| D | POP302 |
| D | MG303 |
| D | TRS304 |
| D | HOH407 |
| site_id | AD5 |
| Number of Residues | 16 |
| Details | binding site for residue POP D 302 |
| Chain | Residue |
| C | TYR180 |
| C | ARG211 |
| C | PHE212 |
| C | GLY213 |
| C | HOH413 |
| D | ASP9 |
| D | ASN57 |
| D | ARG60 |
| D | ARG163 |
| D | ARG169 |
| D | SER171 |
| D | PHE173 |
| D | POP301 |
| D | MG303 |
| D | TRS304 |
| D | HOH407 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 303 |
| Chain | Residue |
| C | HOH413 |
| D | ASP9 |
| D | POP301 |
| D | POP302 |
| D | HOH407 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue TRS D 304 |
| Chain | Residue |
| D | PRO8 |
| D | ASP9 |
| D | TYR26 |
| D | THR51 |
| D | ALA52 |
| D | ASN57 |
| D | PHE68 |
| D | PHE72 |
| D | POP301 |
| D | POP302 |
