5GUL

Crystal structure of Tris/PPix2/Mg2+ bound form of cyclolavandulyl diphosphate synthase (CLDS) from Streptomyces sp. CL190

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016094	biological_process	polyprenol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0045547	molecular_function	dehydrodolichyl diphosphate synthase activity
A	0046872	molecular_function	metal ion binding
B	0016094	biological_process	polyprenol biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0045547	molecular_function	dehydrodolichyl diphosphate synthase activity
B	0046872	molecular_function	metal ion binding
C	0016094	biological_process	polyprenol biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0045547	molecular_function	dehydrodolichyl diphosphate synthase activity
C	0046872	molecular_function	metal ion binding
D	0016094	biological_process	polyprenol biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0045547	molecular_function	dehydrodolichyl diphosphate synthase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue POP A 301

Chain	Residue
A	ASP9
A	TRS304
A	HOH401
A	HOH406
A	HOH411
A	HOH421
B	TYR180
B	ARG211
B	PHE212
B	GLY213
B	HOH425
A	ASN57
A	ARG60
A	ARG163
A	ARG169
A	SER171
A	PHE173
A	POP302
A	MG303

---

site_id	AC2
Number of Residues	12
Details	binding site for residue POP A 302

Chain	Residue
A	ASP9
A	GLY10
A	MET11
A	ARG12
A	ARG13
A	TYR26
A	ARG60
A	POP301
A	MG303
A	TRS304
A	HOH421
B	TYR215

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MG A 303

Chain	Residue
A	ASP9
A	POP301
A	POP302
A	HOH401
A	HOH421

---

site_id	AC4
Number of Residues	11
Details	binding site for residue TRS A 304

Chain	Residue
A	PRO8
A	ASP9
A	MET11
A	TYR26
A	THR51
A	ALA52
A	ASN57
A	PHE68
A	PHE72
A	POP301
A	POP302

---

site_id	AC5
Number of Residues	19
Details	binding site for residue POP B 301

Chain	Residue
A	TYR180
A	ARG211
A	PHE212
A	GLY213
A	HOH412
B	ASP9
B	ASN57
B	ARG60
B	ARG163
B	ARG169
B	SER171
B	PHE173
B	POP302
B	MG303
B	TRS304
B	HOH406
B	HOH408
B	HOH418
B	HOH419

---

site_id	AC6
Number of Residues	13
Details	binding site for residue POP B 302

Chain	Residue
A	TYR215
B	ASP9
B	GLY10
B	MET11
B	ARG12
B	ARG13
B	TYR26
B	ARG60
B	POP301
B	MG303
B	TRS304
B	HOH406
B	HOH419

---

site_id	AC7
Number of Residues	5
Details	binding site for residue MG B 303

Chain	Residue
B	ASP9
B	POP301
B	POP302
B	HOH406
B	HOH419

---

site_id	AC8
Number of Residues	11
Details	binding site for residue TRS B 304

Chain	Residue
B	PRO8
B	ASP9
B	MET11
B	TYR26
B	THR51
B	ALA52
B	ASN57
B	PHE68
B	PHE72
B	POP301
B	POP302

---

site_id	AC9
Number of Residues	13
Details	binding site for residue POP C 301

Chain	Residue
C	ARG13
C	TYR26
C	ARG60
C	POP302
C	MG303
C	TRS304
C	HOH402
C	HOH416
D	TYR215
C	ASP9
C	GLY10
C	MET11
C	ARG12

---

site_id	AD1
Number of Residues	18
Details	binding site for residue POP C 302

Chain	Residue
C	ASP9
C	ASN57
C	ARG60
C	ARG163
C	ARG169
C	SER171
C	POP301
C	MG303
C	TRS304
C	HOH402
C	HOH405
C	HOH408
C	HOH416
D	TYR180
D	ARG211
D	PHE212
D	GLY213
D	HOH406

---

site_id	AD2
Number of Residues	5
Details	binding site for residue MG C 303

Chain	Residue
C	ASP9
C	POP301
C	POP302
C	HOH402
C	HOH416

---

site_id	AD3
Number of Residues	10
Details	binding site for residue TRS C 304

Chain	Residue
C	PRO8
C	ASP9
C	TYR26
C	THR51
C	ALA52
C	ASN57
C	PHE68
C	PHE72
C	POP301
C	POP302

---

site_id	AD4
Number of Residues	13
Details	binding site for residue POP D 301

Chain	Residue
C	TYR215
C	HOH413
D	ASP9
D	GLY10
D	MET11
D	ARG12
D	ARG13
D	TYR26
D	ARG60
D	POP302
D	MG303
D	TRS304
D	HOH407

---

site_id	AD5
Number of Residues	16
Details	binding site for residue POP D 302

Chain	Residue
C	TYR180
C	ARG211
C	PHE212
C	GLY213
C	HOH413
D	ASP9
D	ASN57
D	ARG60
D	ARG163
D	ARG169
D	SER171
D	PHE173
D	POP301
D	MG303
D	TRS304
D	HOH407

---

site_id	AD6
Number of Residues	5
Details	binding site for residue MG D 303

Chain	Residue
C	HOH413
D	ASP9
D	POP301
D	POP302
D	HOH407

---

site_id	AD7
Number of Residues	10
Details	binding site for residue TRS D 304

Chain	Residue
D	PRO8
D	ASP9
D	TYR26
D	THR51
D	ALA52
D	ASN57
D	PHE68
D	PHE72
D	POP301
D	POP302

---