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5GS4

Crystal structure of estrogen receptor alpha in complex with a stabilized peptide antagonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Estrogen receptorpolymer24327751.71UniProt (P03372)
Pfam (PF00104)
Homo sapiens (Human)ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1
2B
(B)
ARG-IAS-ILE-LEU-DNP-ARG-LEU-LEU-GLNpolymer101113.41unidentified
3C, D
(A)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
4E
(A)
ESTRADIOLnon-polymer272.41Chemie (EST)
5F, G
(A, B)
waterwater18.083Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28865.0
Non-Polymers*Number of molecules3
Total formula weight462.3
All*Total formula weight29327.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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