5GON
Structures of a beta-lactam bridged analogue in complex with tubulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 440 | 48966.3 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Tubulin alpha, Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta-2B chain | polymer | 431 | 48391.4 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (Bovine) | Tubulin beta |
| 3 | E (E) | Stathmin-4 | polymer | 136 | 16082.3 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Rat) | Stathmin-like protein B3,RB3 |
| 4 | F (F) | Uncharacterized protein | polymer | 378 | 43549.6 | 1 | UniProt (E1BQ43) | Gallus gallus (Chicken) | |
| 5 | G, W (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | FA, H, IA, N, X (D, A, F, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 7 | AA, GA, HA, I, J... (C, D, A, B) | GLYCEROL | non-polymer | 92.1 | 12 | Chemie (GOL) | |||
| 8 | K, R, U (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 9 | EA, M (D, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 10 | S (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 11 | T (B) | (3R,4R)-4-(4-methoxy-3-oxidanyl-phenyl)-3-methyl-1-(3,4,5-trimethoxyphenyl)azetidin-2-one | non-polymer | 373.4 | 1 | Chemie (6ZR) | |||
| 12 | BA, CA, DA (C) | IMIDAZOLE | non-polymer | 69.1 | 3 | Chemie (IMD) | |||
| 13 | JA, KA, LA, MA, NA... (A, B, C, D, E...) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 254347.4 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 4055.5 | |
| All* | Total formula weight | 258403.0 |
